Hong Kong researchers develop algorithm to foretell diabetic kidney illness danger


A crew of researchers from the Chinese language College of Hong Kong and California-based medical analysis institute Sanford Burnham Prebys has provide you with a brand new computational mannequin to foretell whether or not a affected person with Kind 2 diabetes will develop kidney illness.

The mentioned mannequin, based on a press assertion, measures markers of DNA methylation – a course of that happens when delicate adjustments accumulate within the DNA – from blood samples to test each current kidney operate and the way the kidneys will operate sooner or later. 

It was developed utilizing information from greater than 1,200 sufferers with T2D within the Hong Kong Diabetes Register and has been examined even on a gaggle of Native People with T2D.


It’s mentioned that about half of circumstances of end-stage kidney illness and dialysis round Asia are on account of diabetes. Whereas there was vital progress in treating diabetic kidney illness, it stays tough to evaluate a affected person’s danger of creating the situation utilizing scientific components alone, mentioned Ronald Ma, professor of Diabetes at CUHK College of Medication. 

By combining AI and information, the analysis crew was capable of provide you with a computational mannequin that has the potential to stop kidney illness amongst T2D sufferers and optimise their remedy. 

They’re now working to refine the mannequin whereas additionally increasing its software by incorporating different information that may improve its capacity to foretell different diabetes-related outcomes. A patent software for a similar mannequin has additionally been filed. 


There may be already an present AI-powered instrument that additionally assesses a T2D affected person’s danger of getting kidney illness. Developed by New York-based firm Renalytix AI, KidneyIntelX generates a kidney illness danger rating based mostly on a affected person’s blood pattern and medical historical past.

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